ICRH Kenya

PMTCT & Malaria (closed)

Team members:
Ingrid Inion; Eric Van Marck; Cris Verhofstede; Els Goetghebeur; Kishorchandra Mandaliya; Fabian Mwanyumba; Marleen Temmerman


  • To determine the prevalence and correlates of placental malaria in HIV1 infected and non-infected women, the effect of placental malaria on viral shedding in the genital tract, and the impact of placental malaria on perinatal HIV1 transmission


  • Placental histology was used for detection of malaria parasites


  • Newborns were tested for HIV1-PCR at 1 day and 6 weeks after birth


  • Malaria parasites were found in 9.1 % (34/372) of the HIV1 infected mothers and in 4.3 % (12/277) of HIV1 non-infected women (p= 0.018). No association was found between placental malaria and maternal viral load, or genital tract HIV1-DNA and RNA. Placental malaria did not correlate with in utero (2.9 versus 5.6%, p=0.509) nor peripartal HIV1 transmission (11.5 versus 15.4%, p=0.602)


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